Metabolism of the plant toxins nitropropionic acid and nitropropanol by ruminal microorganisms

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Metabolism of the plant toxins nitropropionic acid and nitropropanol by ruminal microorganisms.

The nitro toxins 3-nitro-1-propionic acid (NPA) and 3-nitro-1-propanol (NPOH), which are found in many leguminous plants, are known to be detoxified by ruminal microorganisms. The rates of the detoxification reactions are critical to acquisition of tolerance to the plants by ruminant animals, but further information is needed about factors which influence reaction rates and about the nature of ...

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Ruminal fluid was obtained over a 4-yr period from cattle on various diets and supplements to determine the effects of different inocula on the microbial degradation of 3-nitropropanol (NPOH), a toxic metabolite in certain Astragalus spp. (Leguminosae). Nitrite (NO2-) metabolism was also studied in vitro because rapid NO2- reduction is required for the overall detoxification of NPOH. Intra-rumi...

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ژورنال

عنوان ژورنال: Applied and Environmental Microbiology

سال: 1993

ISSN: 0099-2240,1098-5336

DOI: 10.1128/aem.59.9.3056-3061.1993